Navigating IBS or adapting to GLP-1 therapy can disrupt your gut microbiome, leading to irregularity, bloating, and daily discomfort. Our MD PhD-formulated Advanced Probiotic & Prebiotic is designed to restore balance gently, strictly avoiding the highly fermentable fibers that trigger sensitive stomachs.
Evidence and quality: what backs this product
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Third-party tested β independent lab verified, made in a cGMP facility.
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FODMAP-conscious formulation β no high-FODMAP fillers such as inulin or chicory root.
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Formulated by Onikepe Adegbola, MD, PhD, a physician-scientist and the founder of Casa de Sante.
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Price: $45.99 (direct from Casa de Sante).
What this product cannot do
The Advanced Probiotic & Prebiotic synbiotic is a dietary supplement, not a medicine. It does not treat, cure or prevent IBS, SIBO, or any disease, it does not replace a low-FODMAP elimination diet or prescribed therapy, and it will not stop symptoms caused by an untreated medical condition. If you have new, severe, or changing GI symptoms, or you are pregnant, nursing, or on prescription medication (including GLP-1 medication), speak to your clinician first.
Frequently asked questions
What is the difference between this and a plain probiotic?
This is a synbiotic: it pairs live probiotic strains with gut-friendly prebiotic fiber, so the strains have a substrate. Our plain probiotic (GI Support, $22.99) has no added prebiotic.
Will the prebiotic fiber make me bloated?
It is chosen to avoid the highly fermentable fibers (inulin, chicory root, FOS) that most often trigger gas in sensitive guts. Start with the lowest suggested serving and build up.
Is it suitable during the low-FODMAP elimination phase?
It is formulated to be FODMAP-conscious, but during a strict elimination phase introduce any supplement one at a time so you can attribute symptoms correctly.
How many capsules a day?
Two capsules daily, with or without food.
Can I take it with GLP-1 medication?
People on GLP-1s commonly use it for regularity as eating patterns change. Confirm with your prescriber first.
Is it third-party tested?
Yes β independent lab verified, made in a cGMP facility.
Product details and price last verified September 17, 2026.